A broccoli-based yogurt could prevent — and even treat — colon cancer, according to a new research.
Researchers in Singapore found that yogurt made with the ‘superfood’ killed 75 percent of tumors in mice, and more than 95 bowel cancer cells grown in a laboratory.
Broccoli contains a cancer-fighting chemical called sulforane, while yogurt contains probiotics – bacteria that helps maintain a natural balance of organisms in the stomach and intestines.
Based on these findings, researchers believe broccoli-based yogurt is a ‘disease busting formula’ that can be used as cancer prevention and to get rid of remaining cells after surgical removal of tumors.
‘One exciting aspect of our strategy is that it just capitalizes on our lifestyle, potentially transforming our normal diet into a sustainable, low-cost therapeutic regimen,’ said researcher Matthew Chang, professor at National University of Singapore.
Professor Matthew Chang and Dr Chun-Loong Ho engineered a harmless form of bacteria called E. coli Nissle, which is found in the gut.
Using genetic techniques they developed it into a probiotic that attached to the surface of bowel cancer cells and secreted an enzyme to convert a substance found in broccoli and other cruciferous vegetables into a potent anti cancer agent.
In tests it killed almost all bowel cancer cells grown in a laboratory.
Then, strikingly, the combination of yogurt and veg killed 75 percent of tumors in mice with the disease.
The tumors that were detected in the rodents were also three times smaller than in a group not fed the mixture.
The researchers see it being used in two ways – both as prevention and to get rid of remaining cancer cells after surgical removal of tumors.
And one day people may be able to take probiotics as a dietary supplement, along with their broccoli, to ward off the disease, or reduce the risk of it returning.
Interestingly, this mixture had no effect on cells from other types of cancer such as breast and stomach cancer.
The researchers, whose study is published in Nature Biomedical Engineering, said with these special bacteria a dose of broccoli a day can keep the cancer doctor away.
Dr Ho added: ‘Mothers are right after all, eating vegetables is important.’
Colon cancer is the second leading cause of cancer-related deaths in the US, and the third most common cancer in men and women, according to the Centers for Disease Control and Prevention.
Despite its prevalence, it’s still unclear what causes colon cancer. However, scientists believe the disease may be linked to western diets, which are typically high in fat and low in fiber.
A 2016 study published in Nature found linked high-fat diets to an increased risk of developing intestinal tumors.
Obesity, red meat alcohol consumption, tobacco use and lack of physical exercise have also been linked to an increased risk of colon cancer, according to the Centers for Disease Control and Prevention.
The US Preventive Services Task Force recommends screening for colon cancer starting at age 50 and continuing to 75.
People with inflammatory bowel disease and/or a family history of colon cancer should get screened earlier.
